LA SOURCE ORIGINALE

How Open Science Can Help Researchers Prepare for the Next Pandemic

NVIDIA Blog ·

Anthony Costa reports an effort to make predicted viral protein-complex structures openly available to scientists. NVIDIA is also releasing the workflow used to produce them, while the dataset labels predictions by confidence.

En un coup d’œil

Passages clés3

Passages attribués et accompagnés du contexte nécessaire à leur vérification. Ouvrez le texte original pour vérifier la source.

open science infrastructure

Open release of viral protein complex structures

Extrait original

To help improve the odds, NVIDIA has joined a coalition of global research organizations, including Google DeepMind and the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI), to release predicted 3D structures for the protein complexes of more than 2,800 viruses — openly available to any scientist, anywhere, through the AlphaFold Database.

Cet extrait ne contient pas de contexte supplémentaire. Consultez la conversation originale.

prediction uncertainty

Protein-complex predictions are labeled by confidence

Extrait original

Predictions in the open dataset are labeled by confidence. The structures show what viral complexes may look like and how individual proteins might interact within a viral proteome.

Cet extrait ne contient pas de contexte supplémentaire. Consultez la conversation originale.

developer tooling

Researchers can use the BioNeMo pipeline for their own targets

Extrait original

NVIDIA is also openly releasing the BioNeMo Structure Prediction Pipeline , the GPU-accelerated workflow used to generate the dataset, so researchers can go from protein sequence to predicted 3D structure for their own targets.

Cet extrait ne contient pas de contexte supplémentaire. Consultez la conversation originale.

Source et méthodologie

Ces points de vue renvoient à leurs sources originales. Les reformulations sont signalées et ne sont pas des citations mot à mot.

Ouvrir la transcription ou les documents sources (s’ouvre dans un nouvel onglet)Signaler un problème